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Remodeling rodent models to mimic human type 1 diabetes

1 Aug 2009

Abstract excerpt

Type 1 diabetes (T1D) occurs when the immune system attacks the insulin-producing beta cells located in the islets of Langerhans within the pancreas. Animal models have played a prominent role in developing an understanding of this disease process, through studies of genetic susceptibility, progression of hyperglycemia, and novel approaches to therapy. Here, we critically evaluate the currently available diabetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19672901
DOI: 10.1002/eji.200939429

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