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Article

Microarray-based STR genotyping using RecA-mediated ligation.

Nucleic acids research - 1 Sept 2010

Herrmann David, Rose Emily, Müller Uwe, Wagner Robert

Abstract excerpt

We describe a novel assay capable of accurately determining the length of short tandem repeat (STR) alleles. STR genotyping is achieved utilizing RecA-mediated ligation (RML), which combines the high fidelity of RecA-mediated homology searching with allele-specific ligation. RecA catalyzes the pairing of synthetic oligonucleotides with one strand of a double-stranded DNA target, in this case a PCR amplicon....

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Identifiers

PMID: 20682559
DOI: 10.1093/nar/gkq657
PMCID: PMC2943619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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