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Article

Rolling circle amplification of DNA immobilized on solid surfaces and its application to multiplex mutation detection.

Genetic analysis : biomolecular engineering - 1 Apr 1999

Hatch A, Sano T, Misasi J, Smith C L

Abstract excerpt

A new method of amplifying short DNA molecules immobilized on a solid support has been developed. This method uses a solid-phase rolling circle replication reaction, termed rolling circle amplification (RCA). The probe consists of a single-stranded DNA primer anchored at the 5' terminus to a soli...

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PMID: 10191983
DOI: 10.1016/s1050-3862(98)00014-x

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10191983-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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