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Article

Evaluation of circular DNA substrates for whole genome amplification prior to forensic analysis.

Forensic science international. Genetics - 1 Mar 2012

Tate Courtney M, Nuñez Ada N, Goldstein Cori A, Gomes Iva, Robertson James M, Kavlick Mark F, Budowle Bruce

Abstract excerpt

Forensic biological evidence often contains low quantities of DNA or substantially degraded DNA which makes samples refractory to genotype analysis. One approach that shows promise to overcome the limited quantity of DNA is whole genome amplification (WGA). One WGA technique, termed rolling circle amplification (RCA), involves the amplification of circular DNA fragments and this study evaluates a single-stranded...

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PMID: 21570374
DOI: 10.1016/j.fsigen.2011.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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