Article
[EGFR and KRAS Gene Mutations in 754 Patients with Resectable Stage I-IIIa Non-small Cell Lung Cancer and Its Clinical Significance].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Sept 2017
Zhao Jing, Gao Jie, Guo Liping, Hu Xiaoxu, Liu Qi, Zhao Jinyin, Liu Licheng, Jiang Jun, Wang Mengzhao, Liang Zhiyong, Xu Yan, Chen Minjiang, Zhang Li, Li Longyun, Zhong Wei
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) and KRAS gene are important driver genes of non-small cell lung cancer (NSCLC). The studies are mainly focused on detection of EGFR gene for advanced NSCLC, and the mutation feature of EGFR and KRAS gene in early NSCLC tissue is unknown. This study aims to investigate the mutations of EGFR and KRAS gene in NSCLC, and the relationship between the genotype and...
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