Article
Development of new HLA-B*3505 genotyping method using Invader assay.
Pharmacogenetics and genomics - 1 Oct 2010
Hosono Naoya, Chantarangsu Soranun, Kiyotani Kazuma, Takata Sadaaki, Tsuchiya Yumiko, Mahasirimongkol Surakameth, Chantratita Wasun, Mushiroda Taisei, Nakamura Yusuke, Kubo Michiaki
Abstract excerpt
Several pharmacogenetic studies have revealed strong associations between specific human leukocyte antigen (HLA) alleles and the susceptibility to drug hypersensitivity. Recently, we reported HLA-B*3505 as a strong genetic biomarker for the nevirapine-induced skin rash in Thai population. Here, we developed a new HLA-B*3505 genotyping method by a combination of the Universal Invader assay and sequence-specific...
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