Article
New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay.
Pharmacogenetics and genomics - 1 Jun 2012
Aoki Masayuki, Hosono Naoya, Takata Sadaaki, Nakamura Yusuke, Kamatani Naoyuki, Kubo Michiaki
Abstract excerpt
BACKGROUND & AIMS: Carbamazepine (CBZ) is widely used for the treatment of epilepsy and other neurological disorders. However, 3-5% of CBZ-treated individuals suffer from cutaneous adverse drug reactions (cADRs). Recently, in a genome-wide association study, HLA-A*31:01 has been reported to be a...
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