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Article

Predictive value of CpG island methylator phenotype for tumor recurrence in hepatitis B virus-associated hepatocellular carcinoma following liver transplantation.

BMC cancer - 2 Aug 2010

Wu Li-Ming, Zhang Feng, Zhou Lin, Yang Zhe, Xie Hai-Yang, Zheng Shu-Sen

Abstract excerpt

BACKGROUND: CpG island methylator phenotype (CIMP), in which multiple genes concordantly methylated, has been demonstrated to be associated with progression, recurrence, as well as overall survival in some types of cancer. METHODS: We examined the promoter methylation status of seven genes including P16, CDH1, GSTP1, DAPK, XAF1, SOCS1 and SYK in 65 cases of HCC treated with LT by methylation-specific PCR. CIMP+...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis B virus

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Share to Neoplasm Recurrence, Local

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Source

Open in PubMed Open full text

Identifiers

PMID: 20678188
DOI: 10.1186/1471-2407-10-399
PMCID: PMC2922195

Genes

AFP
CDH1
GSTP1
SOCS1
SYK
XAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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