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Article

CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma.

Annals of surgical oncology - 1 Jul 2010

Li Binkui, Liu Wenji, Wang Li, Li Meixiang, Wang Jianping, Huang Liang, Huang Pinzhu, Yuan Yunfei

Abstract excerpt

BACKGROUND: CpG island methylator phenotype (CIMP), characterized by simultaneous methylation of multiple tumor suppressor genes (TSGs), has been reported to be associated with biological malignancy in many cancers. Whether CIMP is potentially predictive of clinical outcome in hepatocellular carcinoma (HCC) remains unknown. METHODS: We investigated the methylation status of ten TSGs and CIMP in 115 samples of HCC...

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Topics

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Share to Carcinoma, Hepatocellular
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

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Share to Neoplasm Recurrence, Local

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Source

Identifiers

PMID: 20112070
DOI: 10.1245/s10434-010-0921-7

Genes

GSTP1
MGMT
OPCML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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