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Article

Development and validation of a CIMP-associated prognostic model for hepatocellular carcinoma

1 Sept 2019

Abstract excerpt

BACKGROUND: CpG island methylator phenotype (CIMP), a common biological phenomenon characterized by a subset of concurrently methylated genes, can have an influence on the progression of multiple cancers. However, the potential mechanism of CIMP in hepatocarcinogenesis and its clinical relevance remains only partially understood. METHODS: We used a methylation array from the cancer genome atlas (TCGA) to stratify...

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PMID: 31492561
DOI: 10.1016/j.ebiom.2019.08.064

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