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Article

Correlation of CpG island methylator phenotype with poor prognosis in hepatocellular carcinoma.

Experimental and molecular pathology - 1 Feb 2010

Cheng Yue, Zhang Changsong, Zhao Jun, Wang Chenyang, Xu Yun, Han Zhipeng, Jiang Guocheng, Guo Xianling, Li Rong, Bu Xinxin, Wu Mengchao, Wei Lixin

Abstract excerpt

CpG island methylator phenotype (CIMP), in which multiple genes are concurrently methylated, is an important mechanism in hepatocellular carcinoma development. We determined a hypermethylation profile in hepatocellular carcinoma (HCC). We examined the promoter methylation status of 10 genes in 60...

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Identifiers

PMID: 19879258
DOI: 10.1016/j.yexmp.2009.10.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19879258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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