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Article

The role of CpG island methylator phenotype in the clinical course of hepatocellular carcinoma.

Bioinformatics (Oxford, England) - 22 Dec 2021

Yan Jun, Man Zhongsong, Gao Lu, Cai Lei, Lu Qian, Dong Jiahong

Abstract excerpt

MOTIVATION: Aberrant DNA methylation is strongly associated with heterogeneity in tumors. This study investigated the prognostic value of CpG island methylator phenotype in hepatocellular carcinoma (HCC). RESULTS: A total of 319 HCC samples with 21 121 CpG sites were included in this study and 215 disease-free survival (DFS) and overall survival (OS)-related CpG sites were identified. These CpG sites were divided...

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Identifiers

PMID: 34406374
DOI: 10.1093/bioinformatics/btab600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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