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Article

CpG island methylator phenotype in plasma is associated with hepatocellular carcinoma prognosis.

World journal of gastroenterology - 14 Nov 2011

Liu Ji-Bin, Zhang Yi-Xin, Zhou Shu-Hui, Shi Min-Xin, Cai Jin, Liu Yan, Chen Ke-Ping, Qiang Fu-Lin

Abstract excerpt

AIM: To evaluate the clinical significance of CpG island methylator phenotype (CIMP) in plasma and its association with hepatocellular carcinoma (HCC) progress. METHODS: CIMP status of 108 HCC patients was analyzed using a methylation marker panel in tumor tissues and plasma with methylation-specific polymerase chain reaction. Fifteen samples of non-neoplastic liver tissues and 60 of plasma from healthy persons...

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PMID: 22180715
DOI: 10.3748/wjg.v17.i42.4718
PMCID: PMC3237302

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