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Article

Structural Determinants of Oligomerization of the Aquaporin-4 Channel.

The Journal of biological chemistry - 25 Mar 2016

Kitchen Philip, Conner Matthew T, Bill Roslyn M, Conner Alex C

Abstract excerpt

The aquaporin (AQP) family of integral membrane protein channels mediate cellular water and solute flow. Although qualitative and quantitative differences in channel permeability, selectivity, subcellular localization, and trafficking responses have been observed for different members of the AQP family, the signature homotetrameric quaternary structure is conserved. Using a variety of biophysical techniques, we...

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Source

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Identifiers

PMID: 26786101
DOI: 10.1074/jbc.M115.694729
PMCID: PMC4807272

Genes

AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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