Supertasting and PROP bitterness depends on more than the TAS2R38 gene.

doi:10.1093/chemse/bjm084

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Article

Supertasting and PROP bitterness depends on more than the TAS2R38 gene.

Chemical senses - 1 Mar 2008

Hayes John E, Bartoshuk Linda M, Kidd Judith R, Duffy Valerie B

Abstract excerpt

Polymorphisms in the TAS2R38 gene provide insight to phenotypes long associated 6-n-propylthiouracil (PROP) and phenylthiocarbamide bitterness. We tested relationships between TAS2R38 genotype, taste phenotype, and fungiform papillae (FP) number in 139 females and 59 males (age range 21-60 years), primarily of European ancestry. DNA was analyzed for 3 polymorphic sites, identifying common...

Topics

Adult
Amino Acid Substitution
Female
Gene Frequency
Genotype
Haplotypes
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide
Propylthiouracil
Quinine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, G-Protein-Coupled

Taste

Taste Buds

Taste Threshold

Tongue

Taste Receptors, Type 2

Source

Open in PubMed

Identifiers

PMID: 18209019
DOI: 10.1093/chemse/bjm084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18209019-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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