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Article

Phenotype reversal in induced mutants of CHO cells: analysis of the reversed cell lines.

Mutation research - 1 Jul 1991

Ouellette G, Bradley W E

Abstract excerpt

We have previously shown that descendants of CHO-derived hprt or aprt mutants induced by ethyl methanesulphonate usually undergo a rapid loss of the mutant phenotype during the 10 generations or so of culture in non-selective medium immediately following mutagenesis (Bradley, 1980; Bradley and Laviolette, 1989). We now present an analysis of several mutants and their descendants which have lost the mutant...

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PMID: 2067528
DOI: 10.1016/0027-5107(91)90140-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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