Article
Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients.
Cancer prevention research (Philadelphia, Pa.) - 1 Sept 2010
Dasgupta Santanu, Koch Rachel, Westra William H, Califano Joseph A, Ha Patrick K, Sidransky David, Koch Wayne M
Abstract excerpt
Mitochondrial DNA (mtDNA) mutations were reported in primary head and neck squamous cell carcinoma (HNSCC) patients. However, very little information is available on the mtDNA mutation pattern in the histologically negative surgical margins and tumors of HNSCC patients who experienced tumor recurrence. The present study aimed at understanding the nature and timing of mtDNA mutation in histologically negative...
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