Article
Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma.
Oncotarget - 1 Jul 2012
Uzawa Katsuhiro, Baba Takao, Uchida Fumihiko, Yamatoji Masanobu, Kasamatsu Atsushi, Sakamoto Yosuke, Ogawara Katsunori, Shiiba Masashi, Bukawa Hiroki, Tanzawa Hideki
Abstract excerpt
While circulating tumor-derived molecules have been identified in a variety of malignant tumors, it is sometimes difficult to detect the molecular targets due to the lower serum concentration. We report that evaluation of circulating tumor-derived mitochondrial DNA (mtDNA) seems to have novel eff...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
