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Article

Role of epoxide hydrolase 1 gene polymorphisms in esophageal cancer in a high-risk area in India.

Journal of gastroenterology and hepatology - 1 Aug 2010

Ihsan Rakhshan, Chattopadhyay Indranil, Phukan Rupkumar, Mishra Ashwani K, Purkayastha Joydeep, Sharma Jagannath, Zomawia Eric, Verma Yogesh, Mahanta Jagadish, Saxena Sunita, Kapur Sujala

Abstract excerpt

BACKGROUND AND AIM: Microsomal epoxide hydrolase 1 (EPHX1) is involved in the metabolism of environmental and tobacco carcinogens. Tobacco smoking, betel quid chewing, and alcohol consumption are the major known risk factors for esophageal cancer. The present case-control study evaluated the influence of EPHX1 genetic variations on esophageal cancer susceptibility in 142 patients and 185 healthy controls from a...

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Source

Identifiers

PMID: 20659238
DOI: 10.1111/j.1440-1746.2010.06354.x

Genes

EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Role of epoxide hydrolase 1 gene polymorphisms in esophageal cancer in a high-risk area in India.PMID 20659238Read ↗

Association between microsomal epoxide hydrolase 1 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.Semantic proximity Read ↗

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Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer.Semantic proximity Read ↗

Association between esophageal cancer risk and EPHX1 polymorphisms: a meta-analysis.Semantic proximity Read ↗

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