Article
Association of functionally important polymorphism of microsomal epoxide hydrolase gene (EPHX1) with lung cancer susceptibility.
Cancer investigation - 1 Jul 2011
Tilak Anup R, Kumar Sachin, Jain Meenu, Pant Mohan C, Das Bhudev C, Guleria Randeep, Mittal Balraj, Mathur Neeraj, Kumar Ashwani
Abstract excerpt
Distribution and gene-environment interaction of EPHX1 polymorphism was evaluated in 175 lung cancer patients and 322 controls from north India. Two novel non-synonymous, Lys117Arg and Leu263Phe, and twelve single nucleotide polymorphisms were identified in the present study. Binary logistic regression analysis showed association of polymorphism Tyr113His with increased risk of lung cancer (OR = 2.2, 95% CI =...
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