Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.

Molecular carcinogenesis - 1 Jan 2018

Xu Yinghui, Wang Yanru, Liu Hongliang, Shi Qiong, Zhu Dakai, Amos Christopher I, Fang Shenying, Lee Jeffrey E, Hyslop Terry, Li Xin, Han Jiali, Wei Qingyi

Abstract excerpt

Metzincins are key molecules in the degradation of the extracellular matrix and play an important role in cellular processes such as cell migration, adhesion, and cell fusion of malignant tumors, including cutaneous melanoma (CM). We hypothesized that genetic variants of the metzincin metallopeptidase family genes would be associated with CM-specific survival (CMSS). To test this hypothesis, we first performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAMTS Proteins
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Matrix Metalloproteinase 9

Share to Melanoma

Share to Prognosis

Share to Proportional Hazards Models

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28796414
DOI: 10.1002/mc.22716
PMCID: PMC5716892

Genes

ADAMTS3
MMP16
MMP9
TLL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.PMID 28796414Read ↗

Genetic Variants in WNT2B and BTRC Predict Melanoma Survival.Semantic proximity Read ↗

Deciphering the role of wound healing genes in skin cutaneous melanoma: Insights into expression, methylation, mutations, and therapeutic implications.Semantic proximity Read ↗

Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma-specific survival.Semantic proximity Read ↗

Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.Semantic proximity Read ↗

Association of Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Genetic Variants with Risk and Outcome of Cutaneous Melanoma.Semantic proximity Read ↗

Genetic variants in the integrin signaling pathway genes predict cutaneous melanoma survival.Semantic proximity Read ↗

Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival.Semantic proximity Read ↗

Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations.Semantic proximity Read ↗

Matrix metalloproteinases as diagnostic and prognostic biomarkers in skin cutaneous melanoma and squamous cell carcinomaSemantic proximity Read ↗

Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression.Semantic proximity Read ↗

Genetic variants in the vitamin D pathway genes VDBP and RXRA modulate cutaneous melanoma disease-specific survival.Semantic proximity Read ↗

Matrix Metalloproteinase-9 (MMP-9) polymorphisms in patients with cutaneous malignant melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.