Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term and transgenerational effects of in vitro culture on mouse embryos.

Theriogenology - 1 Mar 2012

Calle Alexandra, Fernandez-Gonzalez Raul, Ramos-Ibeas Priscila, Laguna-Barraza Ricardo, Perez-Cerezales Serafin, Bermejo-Alvarez Pablo, Ramirez Miguel Angel, Gutierrez-Adan Alfonso

Abstract excerpt

The mouse is a convenient model to analyze the impact of in vitro culture (IVC) on the long-term health and physiology of the offspring, and the possible inheritance of these altered phenotypes. The preimplantation period of mammalian development has been identified as an early 'developmental window' during which environmental conditions may influence the pattern of future growth and physiology. Suboptimal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blastocyst
Share to Embryo Culture Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Embryo Transfer

Share to Embryonic Development

Share to Genomic Imprinting

Share to Placenta

Share to Prenatal Exposure Delayed Effects

Source

Identifiers

PMID: 21855990
DOI: 10.1016/j.theriogenology.2011.07.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term and transgenerational effects of in vitro culture on mouse embryos.PMID 21855990Read ↗

Suboptimal in vitro culture conditions: an epigenetic origin of long‐term health effectsSemantic proximity Read ↗

Culture of preimplantation embryos and its long-term effects on gene expression and phenotypeSemantic proximity Read ↗

Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behaviorSemantic proximity Read ↗

The influence of in vitro fertilization and embryo culture on the embryo epigenetic constituents and the possible consequences in the bovine modelSemantic proximity Read ↗

Embryo culture and long-term consequencesSemantic proximity Read ↗

Male mice produced by in vitro culture have reduced fertility and transmit organomegaly and glucose intolerance to their male offspring.Semantic proximity Read ↗

Placental Abnormalities are Associated With Specific Windows of Embryo Culture in a Mouse ModelSemantic proximity Read ↗

Preimplantation embryo programming: transcription, epigenetics, and culture environmentSemantic proximity Read ↗

Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development.Semantic proximity Read ↗

Transcriptional signatures throughout development: the effects of mouse embryo manipulation in vitroSemantic proximity Read ↗

Use of a Mouse In Vitro Fertilization Model to Understand the Developmental Origins of Health and Disease HypothesisSemantic proximity Read ↗

Embryo Culture Conditions and the EpigenomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.