Article
Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells.
Reproductive biology and endocrinology : RB&E - 8 Nov 2006
Ramírez Miguel A, Pericuesta Eva, Fernandez-Gonzalez Raul, Moreira Pedro, Pintado Belen, Gutierrez-Adan Alfonso
Abstract excerpt
BACKGROUND: In the mouse, culture of embryonic stem (ES) cells may decrease their pluripotency and give rise to foetal abnormalities in recipient embryos. These abnormalities are frequently associated with both, chromosome abnormalities or epigenetic alteration of imprinting genes; however, littl...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
