Article
Colorectal cancer risk susceptibility loci in a Swedish population.
Molecular carcinogenesis - 1 Mar 2022
Liu Wen, Mahdessian Hovsep, Helgadottir Hafdis, Zhou Xingwu, Thutkawkorapin Jessada, Jiao Xiang, Wolk Alicja, Lindblom Annika
Abstract excerpt
To search for colorectal cancer (CRC) risk loci, Swedish samples were used for a genome-wide haplotype analysis. A logistic regression model was employed in 2663 CRC cases and 1642 controls in the discovery analysis. Three analyses were done, on all, familial-, and nonfamilial CRC samples and only results with odds ratio (OR) > 1 were analyzed. single nucleotide polymorphism (SNP) analysis did not generate any...
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