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Article

A genome-wide association study of neuroticism in a population-based sample.

PloS one - 9 Jul 2010

Calboli Federico C F, Tozzi Federica, Galwey Nicholas W, Antoniades Athos, Mooser Vincent, Preisig Martin, Vollenweider Peter, Waterworth Dawn, Waeber Gerard, Johnson Michael R, Muglia Pierandrea, Balding David J

Abstract excerpt

Neuroticism is a moderately heritable personality trait considered to be a risk factor for developing major depression, anxiety disorders and dementia. We performed a genome-wide association study in 2,235 participants drawn from a population-based study of neuroticism, making this the largest association study for neuroticism to date. Neuroticism was measured by the Eysenck Personality Questionnaire. After...

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PMID: 20634892
DOI: 10.1371/journal.pone.0011504
PMCID: PMC2901337

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