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Article

SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE.

Translational psychiatry - 25 Oct 2016

Docherty A R, Moscati A, Peterson R, Edwards A C, Adkins D E, Bacanu S A, Bigdeli T B, Webb B T, Flint J, Kendler K S

Abstract excerpt

Biometrical genetic studies suggest that the personality dimensions, including neuroticism, are moderately heritable (~0.4 to 0.6). Quantitative analyses that aggregate the effects of many common variants have recently further informed genetic research on European samples. However, there has been limited research to date on non-European populations. This study examined the personality dimensions in a large sample...

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PMID: 27779626
DOI: 10.1038/tp.2016.177
PMCID: PMC5290344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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