Article
Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion.
Translational psychiatry - 17 Apr 2012
Vinkhuyzen A A E, Pedersen N L, Yang J, Lee S H, Magnusson P K E, Iacono W G, McGue M, Madden P A F, Heath A C, Luciano M, Payton A, Horan M, Ollier W, Pendleton N, Deary I J, Montgomery G W, Martin N G, Visscher P M, Wray N R
Abstract excerpt
The personality traits of neuroticism and extraversion are predictive of a number of social and behavioural outcomes and psychiatric disorders. Twin and family studies have reported moderate heritability estimates for both traits. Few associations have been reported between genetic variants and neuroticism/extraversion, but hardly any have been replicated. Moreover, the ones that have been replicated explain only...
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