Article
Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions.
BMC cancer - 14 Jul 2010
Chaudhary Ajay K, Singh Mamta, Bharti Alok C, Singh Mangal, Shukla Shirish, Singh Atul K, Mehrotra Ravi
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMPs) are enzymes that degrade all the components of extra cellular matrix and collagen. Various types of MMPs are known to be expressed and activated in patients with oral submucous fibrosis (OSMF) as well as head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to asses the association of the single nucleotide polymorphism (SNP) adenosine...
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