Article
The functional (-1171 5A-->6A) polymorphisms of matrix metalloproteinase 3 gene as a risk factor for oral submucous fibrosis among male areca users.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Feb 2006
Tu H-F, Liu C-J, Chang C-S, Lui M-T, Kao S-Y, Chang C-P, Liu T-Y
Abstract excerpt
BACKGROUND: Insertion/deletion (-1171 5A-->6A) polymorphisms in the promoter region of matrix metalloproteinase 3 (MMP3) gene result in different transcriptional activities. MMP3 is able to degrade collagens types II, V, IX, and X, and other extracellular matrix. The functional promoter polymorph...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.