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Article

Matrix metalloproteinase 1, 3, and 9 polymorphisms and esophageal squamous cell carcinoma risk.

Medical science monitor : international medical journal of experimental and clinical research - 13 Nov 2014

Guan Xuan, Wang Xiang, Luo Hao, Wu Jing, Zhang Xiao, Wu Jin

Abstract excerpt

BACKGROUND: Matrix metalloproteinases (MMPs) are multifunctional zinc-dependent proteinases that play a fundamental role in the pathogenesis of tumors. We have analyzed the association between 3 single-nucleotide polymorphisms (SNPs; MMP1 -1607 1G/2G, MMP3 -1612 5A/6A, and MMP9 -1562 C/T) and the risk of esophageal squamous cell carcinoma (ESCC). MATERIAL/METHODS: We investigated these 3 SNPs in 132 patients and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25391977
DOI: 10.12659/MSM.892413
PMCID: PMC4242704

Genes

MMP3
MMP1
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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