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Article

The MMP-2 and MMP-9 promoter polymorphisms and susceptibility to salivary gland cancer.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Radunovic Milena, Nikolic Nadja, Milenkovic Sanja, Tomanovic Nada, Boricic Ivan, Dimitrijevic Milovan, Novakovic Ivana, Basta-Jovanovic Gordana

Abstract excerpt

PURPOSE: Matrix metalloproteinases (MMPs) are a family of endopeptidases that may play an important role in the development of salivary gland cancer (SGC). MMP-2 and MMP-9, members of the gelatinase protein family, are capable of degrading type IV collagen of basement membranes, and their overexpression is often associated with tumor aggressiveness and poor prognosis. The aim of this study was to establish the...

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Share to MMP2 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Matrix Metalloproteinase 2

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Salivary Gland Neoplasms

Source

Identifiers

PMID: 27569079

Genes

MMP2

Provenance

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