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Complement Mediated Endothelial Damage in Thrombotic Microangiopathies

25 Apr 2022

Abstract excerpt

Thrombotic microangiopathies (TMA) constitute a group of different disorders that have a common underlying mechanism: the endothelial damage. These disorders may exhibit different mechanisms of endothelial injury depending on the pathological trigger. However, over the last decades, the potential role of the complement system (CS) has gained prominence in their pathogenesis. This is partly due to the great...

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PMID: 35547236
DOI: 10.3389/fmed.2022.811504

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