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Article

Advances in understanding of pathogenesis of aHUS and HELLP.

British journal of haematology - 1 Nov 2008

Fang Celia J, Richards Anna, Liszewski M Kathryn, Kavanagh David, Atkinson John P

Abstract excerpt

Both atypical haemolytic uraemic syndrome (aHUS) and the HELLP syndrome (haemolytic anaemia, elevated liver enzymes, and low platelets) are thrombotic microangiopathies characterized by microvascular endothelial activation, cell injury and thrombosis. aHUS is a disease of complement dysregulation, specifically a gain of function of the alternative pathway, due to mutations in complement regulatory proteins and...

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Source

Identifiers

PMID: 18691170
DOI: 10.1111/j.1365-2141.2008.07324.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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