Article
[The genetic profile of multiple sclerosis: risk genes and the "dark matter"].
Der Nervenarzt - 1 Jun 2012
Lill C M, Zipp F
Abstract excerpt
Multiple sclerosis (MS) is a genetically complex disease caused by the interplay of genetic and environmental factors. While it shows substantial familial accumulation, there is no evidence for typical Mendelian transmission within families. Instead, MS risk is likely governed by dozens to hundreds of genetic variants, which can also be present in the general population. The strongest genetic risk factor for MS...
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