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Article

Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus.

BMC genomics - 12 Jul 2010

Jeon Jae-Pil, Shim Sung-Mi, Nam Hye-Young, Ryu Gil-Mi, Hong Eun-Jung, Kim Hyung-Lae, Han Bok-Ghee

Abstract excerpt

BACKGROUND: Recent efforts have been made to link complex human traits and disease susceptibility to DNA copy numbers. The leptin receptor (LEPR) has been implicated in obesity and diabetes. Mutations and genetic variations of LEPR gene have been discovered in rodents and humans. However, the association of DNA copy number variations at the LEPR gene locus with human complex diseases has not been reported. In an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20624279
DOI: 10.1186/1471-2164-11-426
PMCID: PMC2996954

Genes

LEPR
LEPROT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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