Article
Copy number variations at LEPR gene locus associated with gene expression and phenotypic traits in Chinese cattle.
Animal science journal = Nihon chikusan Gakkaiho - 1 Mar 2016
Shi Tao, Xu Yao, Yang Mingjuan, Huang Yongzhen, Lan Xianyong, Lei Chuzhao, Qi Xinglei, Yang Xiaoming, Chen Hong
Abstract excerpt
Current evidences show that copy number variations (CNVs) are linked to complex phenotypic traits. Leptin receptor (LEPR) gene plays a critical role in energy homeostasis and fat development and re-sequencing of the cattle genome revealed the CNV region (herein referred to as "I3 DNA") within the LEPR intron 3. In the present study, we qualified copy numbers of I3 DNA within LEPR gene in four cattle breeds...
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