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Article

Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels.

Human molecular genetics - 1 May 2010

Sun Qi, Cornelis Marilyn C, Kraft Peter, Qi Lu, van Dam Rob M, Girman Cynthia J, Laurie Cathy C, Mirel Daniel B, Gong Huizi, Sheu Chau-Chyun, Christiani David C, Hunter David J, Mantzoros Christos S, Hu Frank B

Abstract excerpt

Plasma soluble leptin receptor (sOB-R) levels were inversely associated with diabetes risk factors, including adiposity and insulin resistance, and highly correlated with the expression levels of leptin receptor, which is ubiquitously expressed in most tissues. We conducted a genome-wide associat...

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Source

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Identifiers

PMID: 20167575
DOI: 10.1093/hmg/ddq056
PMCID: PMC2850621

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20167575-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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