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Article

The haplotype identified in LEPR gene is associated with type 2 diabetes mellitus in Northern Chinese.

Diabetes research and clinical practice - 1 Jul 2008

Qu Yanchun, Yang Ze, Jin Feng, Sun Liang, Feng Jie, Tang Lei, Zhang Chuanfang, Zhu Xiaoquan, Shi Xiaohong, Sun Hong, Wang Binyou, Wang Li

Abstract excerpt

Leptin receptor (LEPR) plays an important physiological role in energy metabolism. The study addressed the relationship between leptin receptor gene variations and type 2 diabetes mellitus (T2DM). Three single nucleotide polymorphisms (SNPs) of LEPR gene, Arg109Lys (A/G), Asn656Lys (C/G) and Pro1019Pro (C/T) were detected in a northern population in China. Totally, 317 patients with T2DM and 282 healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18439701
DOI: 10.1016/j.diabres.2008.02.016

Genes

LEPR

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