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Embryonic survival and severity of cardiac and craniofacial defects are affected by genetic background in fibroblast growth factor-16 null mice.

DNA and cell biology - 1 Aug 2010

Lu Shun Yan, Jin Yan, Li Xiaodong, Sheppard Patricia, Bock Margaret E, Sheikh Farah, Duckworth Mary Lynn, Cattini Peter A

Abstract excerpt

Disruption of the X-chromosome fibroblast growth factor 16 (Fgf-16) gene, a member of the FGF-9 subfamily with FGF-20, was linked with an effect on cardiac development in two independent studies. However, poor trabeculation with lethality by embryonic day (E) 11.5 was associated with only one, involving maintenance in Black Swiss (Bsw) versus C57BL/6 mice. The aim of this study was to examine the potential...

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PMID: 20618076
DOI: 10.1089/dna.2010.1024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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