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Article

Effects of genetic background on cardiovascular anomalies in the Ts16 mouse.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2005

Villar A J, Kim J, De Blank P, Gillespie A M, Kozy H M, Ursell P C, Epstein C J

Abstract excerpt

To investigate the genetic contribution to phenotypic variability in aneuploidy, we generated mice with trisomy 16 (Ts16) by mating [Rb(6.16)24Lub x Rb(16.17)7Bnr]F1 males with females from four inbred strains, BALB/cJ, C3H/HeJ, C57BL/6J, and DBA/2J. Among the four Ts16 strains that were generated, there were no significant differences in survival, weight, or length relative to euploid control littermates at...

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PMID: 15580624
DOI: 10.1002/dvdy.20216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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