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Article

Atypical hemolytic uremic syndrome

7 Jul 2010

Abstract excerpt

PURPOSE OF REVIEW: The last few years revealed a molecular distinction between thrombotic thrombocytopenic purpura, a disease characterized by a lack of ADAMTS13 activity, and atypical hemolytic uremic syndrome (aHUS), a disease of complement overactivation. Many different predisposing genetic factors resulting in complement overactivation have been described in aHUS. Additionally, autoantibodies against...

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PMID: 20613506
DOI: 10.1097/moh.0b013e32833cae86

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