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Article

Genetic deficiency in complement component 4b does not alter radiation-induced lung disease in mice.

Radiation research - 1 Feb 2013

Fox Jessica, Bergeron Marie-Eve, Haston Christina K

Abstract excerpt

Previous investigations have shown altered levels of complement components to be associated with radiation-induced lung disease. In this study we aimed to determine whether a deficiency in complement component 4b alters the lung response to irradiation of C57BL/6 mice. The pulmonary phenotype of C57BL/6 C4b(-/-) mice and their wild-type littermates was assessed following an 18 Gy single dose to the thoracic...

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PMID: 23259761
DOI: 10.1667/RR3072.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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