Identification of non-synonymous polymorphisms in the WDSOF1 gene as novel susceptibility markers for low bone mineral density in Japanese postmenopausal women.

doi:10.1016/j.bone.2010.06.017

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Article

Identification of non-synonymous polymorphisms in the WDSOF1 gene as novel susceptibility markers for low bone mineral density in Japanese postmenopausal women.

Bone - 1 Sept 2010

Urano Tomohiko, Shiraki Masataka, Usui Takahiko, Sasaki Noriko, Ouchi Yasuyoshi, Inoue Satoshi

Abstract excerpt

Genetic factors are important for the development of osteoporosis. During the search for novel markers of single-nucleotide polymorphisms (SNPs) associated with bone mineral density (BMD) by performing a large-scale SNP screen with 251 Japanese postmenopausal women utilizing 50K SNP array, we here focused on the rs1370005 in the WD repeats and SOF1 domain-containing (WDSOF1) gene because we could found common...

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PMID: 20601284
DOI: 10.1016/j.bone.2010.06.017

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