Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the I264T variant in the sulfide quinone reductase-like (SQRDL) gene with osteoporosis in Korean postmenopausal women.

PloS one - 1 Jan 2015

Jin Hyun-Seok, Kim Jeonghyun, Park Sangwook, Park Eunkuk, Kim Bo-Young, Choi Vit-Na, Yoo Young-Hyun, Kim Bom-Taeck, Jeong Seon-Yong

Abstract excerpt

To identify novel susceptibility variants for osteoporosis in Korean postmenopausal women, we performed a genome-wide association analysis of 1180 nonsynonymous single nucleotide polymorphisms (nsSNPs) in 405 individuals with osteoporosis and 722 normal controls of the Korean Association Resource cohort. A logistic regression analysis revealed 72 nsSNPs that showed a significant association with osteoporosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcification, Physiologic
Share to Core Binding Factor Alpha 1 Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen Sulfide

Share to Osteoclasts

Share to Osteoporosis, Postmenopausal

Share to Oxidoreductases Acting on Sulfur Group Donors

Share to Primary Cell Culture

Share to Quinone Reductases

Source

Open in PubMed Open full text

Identifiers

PMID: 26258864
DOI: 10.1371/journal.pone.0135285
PMCID: PMC4530967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the I264T variant in the sulfide quinone reductase-like (SQRDL) gene with osteoporosis in Korean postmenopausal women.PMID 26258864Read ↗

Genetic susceptibility of postmenopausal osteoporosis on sulfide quinone reductase-like gene.Semantic proximity Read ↗

An integrative study ascertained SOD2 as a susceptibility gene for osteoporosis in Chinese.Semantic proximity Read ↗

Identification of potential pathogenic genes associated with osteoporosisSemantic proximity Read ↗

Mediating oxidative stress through the Palbociclib/miR-141-3p/STAT4 axis in osteoporosis: a bioinformatics and experimental validation studySemantic proximity Read ↗

Bioinformatics analysis of oxidative phosphorylation-related differentially expressed genes in osteoporosisSemantic proximity Read ↗

The osteoporosis susceptible SNP rs4325274 remotely regulates the SOX6 gene through enhancers.Semantic proximity Read ↗

Association of osteoporosis susceptibility genes with bone mineral density and bone metabolism related markers in Koreans: the Chungju Metabolic Disease Cohort (CMC) study.Semantic proximity Read ↗

Association of rs4516035 Polymorphism with Osteoporosis in the Southeastern Iranian Population: A Case-Control Study.Semantic proximity Read ↗

Functional relevance for associations between osteoporosis and genetic variants.Semantic proximity Read ↗

4q22.1 contributes to bone mineral density and osteoporosis susceptibility in postmenopausal women of Chinese Han population.Semantic proximity Read ↗

The Polymorphism at PLCB4 Promoter (rs6086746) Changes the Binding Affinity of RUNX2 and Affects Osteoporosis Susceptibility: An Analysis of Bioinformatics-Based Case-Control Study and Functional Validation.Semantic proximity Read ↗

Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.