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Article

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance.

Annals of the rheumatic diseases - 1 May 2011

Valdes Ana M, Evangelou Evangelos, Kerkhof Hanneke J M, Tamm Agu, Doherty Sally A, Kisand Kalle, Tamm Ann, Kerna Irina, Uitterlinden Andre, Hofman Albert, Rivadeneira Fernando, Cooper Cyrus, Dennison Elaine M, Zhang Weiya, Muir Kenneth R, Ioannidis John P A, Wheeler Margaret, Maciewicz Rose A, van Meurs Joyce B, Arden Nigel K, Spector Tim D, Doherty Michael

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 20870806
DOI: 10.1136/ard.2010.134155
PMCID: PMC4699799

Genes

GDF5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance.PMID 20870806Read ↗

An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage.Semantic proximity Read ↗

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility.Semantic proximity Read ↗

A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.Semantic proximity Read ↗

A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand.Semantic proximity Read ↗

Association between GDF5 rs143383 polymorphism and knee osteoarthritis: an updated meta-analysis based on 23,995 subjects.Semantic proximity Read ↗

Polymorphisms in the Growth Differentiation Factor 5 (GDF 5) Gene in Knee Osteoarthritis.Semantic proximity Read ↗

Association between GDF5 rs143383 genetic polymorphism and musculoskeletal degenerative diseases susceptibility: a meta-analysis.Semantic proximity Read ↗

A rare variant in the osteoarthritis-associated locus GDF5 is functional and reveals a site that can be manipulated to modulate GDF5 expression.Semantic proximity Read ↗

Association Between the SNP rs143383 + 104T/C in the GDF5 Gene and the Risk of Knee Osteoarthritis in a Population from Northern Mexico-A Case-Control Study.Semantic proximity Read ↗

The association of growth differentiation factor 5 rs143383 gene polymorphism with osteoarthritis: a systematic review and meta-analysis.Semantic proximity Read ↗

Rs143383 in the growth differentiation factor 5 (GDF5) gene significantly associated with osteoarthritis (OA)-a comprehensive meta-analysis.Semantic proximity Read ↗

Association between the +104T/C polymorphism in the 5'UTR of GDF5 and susceptibility to knee osteoarthritis: a meta-analysis.Semantic proximity Read ↗

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