Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A specific haplotype in potential miRNAs binding sites of secreted frizzled-related protein 1 (SFRP1) is associated with BMD variation in osteoporosis.

Gene - 30 Nov 2018

Amjadi-Moheb Fatemeh, Hosseini Seyed Reza, Kosari-Monfared Mohadeseh, Ghadami Elham, Nooreddini Hajighorban, Akhavan-Niaki Haleh

Abstract excerpt

PURPOSE: Osteoporosis is an important multifactorial disease which is largely influenced by Wnt signaling pathway. Considering regulatory single nucleotide polymorphisms in Wnt signaling pathway may pave the road of understanding the genetic basis of predisposition to osteoporosis. The aim of this study was to determine the possible association between variants of SFRP1 and WNT5b, and osteoporosis incidence risk....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Bone Density

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Femur Neck

Share to Intercellular Signaling Peptides and Proteins

Share to Lumbar Vertebrae

Share to MicroRNAs

Share to Osteoporosis

Share to Wnt Proteins

Source

Identifiers

PMID: 30055306
DOI: 10.1016/j.gene.2018.07.061

Genes

SFRP1

Variants

rs1127379
rs3242
rs3803164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A specific haplotype in potential miRNAs binding sites of secreted frizzled-related protein 1 (SFRP1) is associated with BMD variation in osteoporosis.PMID 30055306Read ↗

Association of single nucleotide polymorphisms in secreted frizzled-related protein 1 gene with bone mineral density in Japanese women.Semantic proximity Read ↗

Association between polymorphisms in sclerostin, dickkopfs and secreted frizzled-related protein genes and bone mineral density in postmenopausal Korean women.Semantic proximity Read ↗

[Epidemiology of bone and joint disease - the present and future - . Molecular epidemiology of osteoporosis].Semantic proximity Read ↗

Associations between WNT signaling pathway-related gene polymorphisms and risks of osteoporosis development in Chinese postmenopausal women: a case-control study.Semantic proximity Read ↗

Identification of Potential Therapeutic Targets and Molecular Regulatory Mechanisms for Osteoporosis by Bioinformatics MethodsSemantic proximity Read ↗

Case Control Association Study of WNT Signaling Pathway-related Genes and Osteoporosis Risk Among Chinese Postmenopausal WomenSemantic proximity Read ↗

[Wnt signaling molecules related to osteoporosis].Semantic proximity Read ↗

[Genetics of osteoporosis].Semantic proximity Read ↗

Association between polymorphisms in Wnt signaling pathway genes and bone mineral density in postmenopausal Korean women.Semantic proximity Read ↗

Single-nucleotide polymorphism rs10036727 in the SLIT3 gene is associated with osteoporosis at the femoral neck in older Mexican postmenopausal women.Semantic proximity Read ↗

Recent genetic discoveries in osteoporosis, sarcopenia and obesity.Semantic proximity Read ↗

Differential gene expression orchestrated by transcription factors in osteoporosis: bioinformatics analysis of associated polymorphism elaborating functional relationships.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.