Progenitor properties of symmetrically dividing Drosophila neuroblasts during embryonic and larval development.

Abstract excerpt

Asymmetric cell division generates two daughter cells of differential gene expression and/or cell shape. Drosophila neuroblasts undergo typical asymmetric divisions with regard to both features; this is achieved by asymmetric segregation of cell fate determinants (such as Prospero) and also by asymmetric spindle formation. The loss of genes involved in these individual asymmetric processes has revealed the roles...

Topics

• Animals
• Cell Differentiation
• Cell Division
• Cell Proliferation
• Drosophila Proteins
• Drosophila melanogaster
• Embryonic Development
• Gene Expression Regulation, Developmental
• Genes, Insect
• Larva
• Models, Biological
• Mutant Proteins
• Mutation
• Nerve Tissue Proteins
• Neurons
• Nuclear Proteins
• Stem Cells
• Time Factors