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Article

Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobe.

Development (Cambridge, England) - 1 Sept 2010

Egger Boris, Gold Katrina S, Brand Andrea H

Abstract excerpt

The proper balance between symmetric and asymmetric stem cell division is crucial both to maintain a population of stem cells and to prevent tumorous overgrowth. Neural stem cells in the Drosophila optic lobe originate within a polarised neuroepithelium, where they divide symmetrically. Neuroepithelial cells are transformed into asymmetrically dividing neuroblasts in a precisely regulated fashion. This cell fate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20685734
DOI: 10.1242/dev.051250
PMCID: PMC2926952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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