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Article

Risk of infection and sepsis in severely injured patients related to single nucleotide polymorphisms in the lectin pathway.

The British journal of surgery - 1 Dec 2013

Bronkhorst M W G A, Lomax M A Z, Vossen R H A M, Bakker J, Patka P, van Lieshout E M M

Abstract excerpt

BACKGROUND: Infectious complications remain a serious threat to patients with multiple trauma. Susceptibility and response to infection is, in part, heritable. The lectin pathway plays a major role in innate immunity. The aim of this study was to assess whether single nucleotide polymorphisms (SNPs) in three key genes within the lectin pathway affect susceptibility to infectious complications in severely injured...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24227370
DOI: 10.1002/bjs.9319

Genes

FCN2
MASP2
MBL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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