Article
Mannose-binding lectin gene variants and infections in patients receiving autologous stem cell transplantation.
BMC immunology - 3 May 2014
Moreto Ana, Fariñas-Alvarez Concepción, Puente Maria, Ocejo-Vinyals Javier Gonzalo, Sánchez-Velasco Pablo, Horcajada Juan Pablo, Batlle Ana, Montes Carmen, Santos Francisca, Conde Eulogio, Fariñas Maria-Carmen
Abstract excerpt
BACKGROUND: Serious infections are common in patients undergoing autologous stem cell transplantation (ASCT) mainly because of the effects of immunosuppression. The innate immune system plays an important role in the defense against different infections. Mannose binding lectin (MBL) is a central molecule of the innate immune system. There are several promoter polymorphisms and structural variants of the MBL2 gene...
Topics
Join the communities discussing this publication.
